Hallway gossip between Ras and PI3K pathways.
نویسنده
چکیده
In this issue of Blood, Goodwin et al investigate the pathogenesis of juvenile myelomonocytic leukemia (JMML), demonstrating that mutant Shp2 induces granulocyte macrophage-colony-stimulating factor (GM-CSF) hypersensitivity and that the p110δ subunit of phosphatidylinositol 3-kinase (PI3K) further promotes this dysregulation
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ورودعنوان ژورنال:
- Blood
دوره 123 18 شماره
صفحات -
تاریخ انتشار 2014